- #Freestyle libre flash glucose monitoring system invasive serial
- #Freestyle libre flash glucose monitoring system invasive skin
- #Freestyle libre flash glucose monitoring system invasive portable
Furthermore, whether treatment decisions based on GCs obtained with the FGMS differ from those derived using a PBGM has not been investigated in dogs. 11 However, studies evaluating the clinical use of FGMS in the monitoring of dogs with DM are lacking. In contrast to other CGMS, this FGMS does not require calibration and the device is accurate when evaluating IG in dogs with diabetes mellitus and is well tolerated by dogs.
#Freestyle libre flash glucose monitoring system invasive skin
The device measures IG levels on a minute-by-minute basis via a disc shaped sensor with a small catheter inserted under the skin that can record measurements for up to 14 days. Recently, a novel flash glucose monitoring system (FGMS) has been licensed for the use in a number of countries. The devices used in most previous veterinary studies have a number of limitations not limited to the need for frequent calibration with circulating blood glucose, but also having a limited monitoring period. 2, 5- 11 CGMS typically consist of a sensor which measures interstitial glucose (IG) and relays the recorded measurements to a transmitter. 3, 4Ĭontinuous glucose monitoring systems (CGMS) are used routinely in human diabetic patients and several studies have demonstrated their accuracy and clinical utility in veterinary medicine.
#Freestyle libre flash glucose monitoring system invasive serial
This last aspect represents an important limitation because of the variability of serial blood glucose curves in dogs and humans. 2Additionally, in-hospital BGCs are time consuming, expensive and do not allow the assessment of glycemia on consecutive days. 1 This method has some disadvantages such as the need for repeated venipuncture, that can be stressful and painful for the animal, but also carries the risk of missing the blood glucose peak or nadir if they fall between 2 sampling times. Evaluation of BGCs allows clinicians to determine glucose nadir, time to nadir, mean blood glucose concentration as well as assessing the degree of variation in blood glucose concentration.
#Freestyle libre flash glucose monitoring system invasive portable
1 Typically, BGCs are conducted in a hospital setting or at home and involve 1-to-2 hourly blood sampling with a portable blood glucose meter (PBGM) over an 8 to 12 hour period. Tools available to veterinarians for monitoring the response of diabetic dogs to treatment include clinical signs, body weight, glycated proteins levels, and blood glucose curves (BGCs) among others. 1 Dogs with DM are treated with exogenous insulin and require regular monitoring to ensure appropriate dosing.
The FGMS allows a more accurate identification of the glucose nadirs and hypoglycemic episodes compared to the use of a PBGM and assessment of day-to-day variations in glycemic control.ĭiabetes mellitus (DM) is a common endocrine disease of dogs characterized by an absolute or relative deficiency of insulin. Insulin dose adjustments based on BGCs can be suboptimal.
The individual FGMS scans and PBGM identified 60% and 9% of low IG/hypoglycemic episodes, respectively. In comparison, concordant glucose nadirs were identified in 14/34 (41%) BGCs using PBGM. Glucose nadirs were detected in 34/43 (79%) of Ambulatory Glucose Profile (AGP) reports of the FGMS. There was good concordance between insulin dose recommendations based on FGMS and PBGM generated GCs and IGCs obtained in the 2 different environments on 2 consecutive days, but almost absent concordance between IGCs obtained on 2 consecutive days at home. Comparisons of insulin dose recommendations based on the in-hospital GCs acquired using FGMS and a PBGM, consecutive-day interstitial GCs (IGCs) acquired at home using the FGMS, and consecutive-day, home vs hospital IGCs acquired using the FGMS were made using concordance analysis. Dogs with diabetes mellitus on insulin treatment for at least 1 month were included. To compare the clinical utility of FGMS against blood glucose curves (BGCs) obtained with a portable blood glucose meter (PBGM) in monitoring DD. It is not known if this system is clinically useful in monitoring DD.
Flash glucose monitoring system (FGMS FreeStyle Libre) was recently validated for use in diabetic dogs (DD).